IndexWhat is amyloid beta?How does amyloid beta affect Alzheimer's disease?How can amyloid beta and Alzheimer's? In the world of medicine, Alzheimer's disease is considered the enemy of mental health. Sleep deprivation or lack of sleep is also a recognized factor when talking about healthy state of mind. In various studies, sleep disorders have been linked to several degenerative mental illnesses. To expand on this point, “researchers reported that biomarkers of amyloid beta (A?), the plaque-forming peptides associated with Alzheimer's disease, increase over time in older adults with OSA in proportion to the severity of OSA. Therefore, individuals with more apneas per hour had greater accumulation of brain amyloid over time.” Based on data from studies that have reported the increase in Alzheimer's disease in patients with sleep apnea, there is a potential positive correlation between sleep cycle functioning and an individual's susceptibility to the problem. In recent years many studies have been dedicated to discovering how Alzheimer's is formed. Other professionals state that “it is widely believed that the pathogenesis of Alzheimer's disease (AD) is driven by the production and deposition of the amyloid beta (Abeta) peptide.” Over time, the buildup of these dangerous cell plaques inhibits the normal functions of the mind. Plaque is well known for clogging the arteries and veins of the bloodstream and cardiovascular system. Today, plaque or beta-amyloid peptide is a candidate for the position of leading cause of dementia and Alzheimer's-level dementia. Indeed, “for many years, researchers have been perplexed by the weak or nonexistent correlation between the amount of neurotic plaque pathology in the human brain and the degree of clinical dementia.” By understanding how Alzheimer's works, people who are worried about the problem have more opportunities to put their mind at ease. Beyond that, understanding the functions of plaque and beta-amyloid will only deepen the knowledge of those who wish to avoid Alzheimer's. Say no to plagiarism. Get a tailor-made essay on "Why Violent Video Games Shouldn't Be Banned"? Get an original essay What is amyloid beta? Plaque found in an individual's body's bloodstream is used to prevent infections and provide a barrier from outside elements trying to enter the body. In some cases, plaque can become harmful in some conditions, mainly due to the way it restricts blood flow. Due to the increase in Alzheimer's-related problems, more attention is being paid to what are considered major contributors to Alzheimer's. To give some perspective, “AD is a neurodegenerative disease that afflicts approximately five million older Americans. OSA is even more common, affecting 30 to 80 percent of older adults, depending on how OSA is defined.” The body's defense systems are much weaker in older individuals, making them more likely to develop a plaque-related problem. Older adults are more easily affected by common problems that occur throughout the world, and these problems include heavy plaque buildup. Plaque particles function like scales or platelets that flow into the bloodstream, clumping together as the body repairs. To elaborate on this topic, “plaques form when protein pieces called beta-amyloid clump together. Beta-amyloid comes from a larger protein found in the fatty membrane surrounding nerve cells. In a sense, amyloid beta plaque cells are an isotope that isgenerates from their more helpful and useful counterparts. Beta-amyloid plaque cells function incredibly differently from normal plaque cells in the body. For example, “the most harmful form of beta-amyloid may be made up of clusters of a few pieces rather than the plaques themselves. The small clumps can block cell-to-cell signaling at synapses. They can also activate immune system cells that turn on inflammation and devour disabled cells." Instead of blocking harmful bacteria, beta-amyloid plaque cells do the opposite of what is needed for a functioning body. The next question the researchers asked was about the relationship between beta-amyloid cells and the progression of Alzheimer's. How does amyloid beta affect Alzheimer's? Today, sleep disorders have become recognized as a serious health threat, despite how harmless these conditions may appear. . The sleep process consists of a few different steps, each of which helps create adequate rest. Sleep conditions such as sleep apnea and sleep walking can be more harmful to your condition than expected. In fact, “Several studies have suggested that sleep disturbances may contribute to amyloid deposits and accelerate cognitive decline in individuals at risk for AD,” said senior author Ricardo S. Osorio of New York University School of Medicine. Studies into sleep disorders believe they have found a link between the amount of plaque buildup in an individual and the risk of developing Alzheimer's disease. Despite this beneficial finding, there is still some speculation about how accurate these results cause different problems, but Alzheimer's disease is a more complicated health condition than most people realize. Furthermore, “the purpose of this study was to investigate associations between OSA severity and changes in AD biomarkers longitudinally, particularly whether amyloid deposits increase over time in individuals. Healthy older participants with OSA” OSA is a more aggressive form of sleep apnea, which creates more health problems for people with the condition. Patients also need to understand that even the most basic forms of sleep apnea can cause severe plaque buildup if left untreated blood flow, thus impeding the natural movements of platelets in the bloodstream One study found “that more than half of the participants had OSA, including 36.5% with mild OSA and 16.8% with moderate to severe OSA” All participants in the study conducted above were older individuals; people who were more likely to get a dementia-related disorder. As sleep apnea causes plaque buildup, OSA is more harmful than normal amounts of sleep apnea. , it can be understood that the accumulation of plaques. may be a major cause of Alzheimer's. After learning how plaque buildup works, a patient at risk for Alzheimer's or even normal sleep apnea has a better opportunity to find a positive treatment method. How can beta amyloid and Alzheimer's be treated? condition is linked to sleep disorders such as sleep apnea or OSA, then the treatment methods are clear. Staying healthy in the present is one of the best opportunities an individual has to prevent diseases such as Alzheimer's and dementia. Essentially, it is the little things an individual does every day to culminate in a healthy lifestyle. On another note, “the high prevalence of OSA found by the study in these cognitively normal older participants and the link between OSA and amyloid load in these very early stages of AD pathology.” It is the elderly who suffer most of the damage.