Cancer is a disease that plagues our society and is at the forefront of scientific research around the world. There have been many advances in cancer research and the development of therapies or potential cures. However, cancer remains one of the major health problems to this day. There are many unanswered questions about this disease, and even with extensive research, they usually lead to more questions. Cancer stem cells are a type of cancer cell that plays an important role in determining the potential aggressive behavior of cancer. Cancer stem cells have taken the research world by storm and, although hotly debated, could potentially lead to the development of cancer therapies and impact the future of cancer treatment, or even a cure. To understand cancer stem cells, you must first understand stem cells in general. The idea of cancer stem cells was proposed more than 100 years ago, but has recently become a focal point due to the similarities they share with normal stem cells. The idea of cancer stem cells gave rise to research because subcomponents of stem cells have been identified in tumors of the breast, brain and other organs. The parallels between cancer stem cells and stem cells have led to a theory or hypothesis about cancer stem cells and hopefully could one day lead to the eradication of cancer. Stem cells are controversial and constitute a hotly debated research area of biology. They are basically the main cells of the body and embody important characteristics. According to Jordan, Guzman, and Noble, “stem cells have three distinctive properties: self-renewal, the ability to develop into multiple lineages, and the potential to proliferate widely” (1253). The feature of… middle of the card… is sometimes a temporary means to an end, “Tumors that appear to have been successfully eliminated immediately after treatment may and often do recur at a later time ". new site” (Goldthwaite, 93). Research and development is focusing on the ability to directly target cancer stem cells and avoid damaging healthy tissue. Goldthwaite also shows us that, “If the CSC hypothesis proves correct, then a strategy designed to selectively target CSCs could potentially stop tumor “seeds” before they have a chance to germinate and spread” (93). Eliminating the cancer stem cells responsible for tumor growth could potentially cure a patient. Leaving the cancer stem cells and simply destroying the tumor is not beneficial. Having a clear understanding of how cancer stem cells escape therapies can also lead to more effective cancer treatments.
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